FAQs About the Estriol Hormone

If you have never undergone hormone-replacement therapy (HRT), you’ve probably never heard of the estriol hormone. Once thought of as useless and discarded by the medical community, this mysterious type of estrogen has re-emerged into the forefront of the HRT community. This is for good reason, and we will be exploring the many therapeutic qualities this re-discovered hormone has to offer.

What is the Estriol Hormone?

Estriol is one of the three principal endogenous estrogens produced by the body. The other two hormones produced are estradiol and estrone. Once thought of as the weakest of the three due to its lack of measured estrogenic activity, the estriol hormone has now been proven through new research starting in the 1960s to have many therapeutic qualities. This discovery is attributed to the realization that estriol has lower risks than horse-derived and synthetic hormones that were available at the time.

Some studies have suggested that the estriol hormone helps in the relief of menopausal symptoms. The hormone has also shown to be effective in restoring health to bones from degenerative bone conditions such as osteoporosis and in the treatment of urinary tract conditions.

How Does the Estriol Hormone Work?

The many health benefits of estriol can be partially explained by the mixed anti-estrogenic and pro-estrogenic qualities that it has. When estriol is combined with estradiol, the estradiol-specific stimulation on cells is lessened. When administered alone, however, the estriol hormone displays more complete pro-estrogenic qualities, which explains the benefits it has for menopausal women.

How is Estriol Measured?

Hormones that are found naturally in the body are secreted in pulses. This is in contrast to hormones that are replaced orally or transdermally. Instead of being released in pulses, these hormones produce initial high measurable levels that will decline throughout the day. This makes collecting measurements via saliva or serum testing unreliable because there are simply too many variables.

Due to these variables, the most accurate way to measure the secreted estriol levels in the body is via 24-hour urine collection. Collecting for a whole day eliminates the fluctuations and ensures the correct measurement is recorded.

Want More Information?

Hormone replacement therapy requires a prescription and approval from a qualified medical professional. To set up your first consultation, reach out to our team at Peak Medical Clinic. We have offices located in Medford, OR, Eugene, OR, Klamath Falls, OR and Roseburg, OR. Contact us today to book your appointment!

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